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Funded Projects

Our laboratory is able to conduct its research thanks to funding by the August Pi i Sunyer Biomedical Research Institute (IDIBAPS), along with the generous support of institutions such as the Spanish Biomedical Research Centre in Diabetes and Associated Metabolic Disorders (CIBERDEM), and the Secretary for Universities and Research of the Ministry of Economy and Knowledge of the Government of Catalonia.

Our research team has been awarded competitive funding for specific projects from national and international government agencies, as well as from private foundations. In addition, we have forged several industry partnerships. Below please find a list of active funded projects that are currently underway at the Diabetes and Obesity Research Laboratory:

Regulación y función de microRNAs en islotes pancreáticos
Funding body: Ministerio de Ciencia e Innovación
Principal investigator: JM. Servitja
Dates: 2011-2013

Epigenetic control of gene expression in pancreatic islets
Funding body: European Foundation for the Study of Diabetes (EFSD) /Lilly Fellowship Programme
Principal investigator: JM. Servitja
Dates: 2010-2013

Papel de la demetilasa de histonas LSD1 en la adipogénesis
Funding body: Ministerio de Ciencia e Innovación
Principal investigator: M. Párrizas
Dates: 2010-2013

Respuesta antioxidativa alterada en células endoteliales expuestas a glucosa oscilatoria: papel de Nrf2
Funding body: Instituto de Salud Carlos III
Principal investigator: A. Ceriello
Dates: 2011-2013

Implicación del enzima BACE 2 en el mecanismo por el cual el péptido pancreático humano IAPP induce alteraciones de la célula beta pancreática en la diabetes de tipo 2
Funding body: Instituto de Salud Carlos III
Principal investigator: Ana Novials
Dates: 2012-2014

Mecanismos reguladores de la proliferación de la célula beta pancreática en el diseño de nuevas estrategias terapéuticas en diabetes
Funding body: Ministerio de Economía y Competitividad, Instituto de Salud Carlos III
Principal investigator: Rosa Gasa
Dates: 2013-2015

Role of neuropeptide alpha-MSH in glucose homeostasis control: interrogating hypothalamic circuits as a potential therapeutical approach for type-2 diabetes, Ministerio de Ciencia e Innovación
Funding body: Instituto de Salud Carlos III
Principal investigator: Marc Claret
Dates: 2014-2016

Estudio del papel de la fusión mitocondrial en neuronas hipotalámicas sobre el control del apetito y la regulación del peso corporal: Opa 1 como potencial diana terapéutica para el tratamiento de la obesidad
Funding body: Fundación BBVA
Principal investigator: Ramon Gomis
Dates: 2015-2016

Mecanismos reguladores de la proliferación de la célula beta pancreática en el diseño de nuevas estrategias terapéuticas en diabetes
Funding body: Ministerio de Economía y Competitividad
Principal investigator: Ramon Gomis
Dates: 2014-2016

Menjar bé, envellir millor: avui sardina
Funding body: RecerCaixa
Principal investigator: Ramon Gomis
Dates: 2014-2016

Impacte de la dieta rica en sardina en el control metabòlic de la diabetis tipus 2, Ajut a la recerca en diabetis Gonçal Lloveras i Vallès
Funding body: Associació Catalana de Diabetis
Principal investigator: Ramon Gomis
Dates: 2014-2016

Trasplantament cel·lular i diabetes mellitus: com millorar la revascularització i la supervivència de l’empelt, Recerca bàsica 2014
Funding body: Acadèmia de Ciències Mediques i de la Salut de Catalunya i de Balears (2014-2016)
Principal investigator: Ramon Gomis

Cátedra AtraZeneca de Innovación en Diabetes
Funding body: AstraZeneca
Principal investigator: Ramon Gomis

Diabetis experimental, investigació cel·lular i molecular en models de diabetis experimental, Direcció General de Recerca
Funding body: Generalitat de Catalunya (2014-2016)
Principal investigator: Ramón Gomis

Understanding obesity (Ob), metabolic syndrome (MetS), type 2 diabetes (T2DM) and fatty liver disease (FL): a multidisciplinary approach
Funding body: ISCIII-Ministerio de Economía y Competitividad (2015-2017)
Principal investigator: Ramón Gomis

Molecular determinants of beta cell plasticity in diabetes: sodium tungstate effects
Funding body: Spanish Ministry of Science and Innovation (MICINN).

Plasticity of beta cell mass and type 2 diabetes
Funding body: Botín Foundation

Implication of BACE2 in the mechanism of hIAPP-induced β-cell dysfunction in T2DM (PI11/00679)
Funding body: Carlos III Health Institute. Spanish Ministry of Science and Innovation (MICINN).

Role of hypothalamic mitochondrial fusion in appetite and body weight control: potential therapeutical target for the treatment of obesity
Funding body: RecerCaixa

MicroRNAs hipotalámicos y regulación del metabolismo energético: posibles dianas terapéuticas para el tratamiento de la obesidad y la diabetes
Funding body: Carlos III Health Institute. Spanish Ministry of Science and Innovation (MICINN).

Role of miRNAs in hypothalamic populations of neurons upon energy and glucose homeostasis: potential targets for obesity and diabetes treatment
Funding body: Carlos III Health Institute. Spanish Ministry of Science and Innovation (MICINN).

Descifrando la respuesta integral capaz de restituir la normoglucemia en ratones con diabetes tipo 2 debido a cambios en su estilo de vida (dieta y/o ejercicio) (BFU2011-24679)
Funding body: Spanish National R&D&I Plan 2008-2011

Molecular mechanisms underlying the development of insulin resistance: role of betaine supplementation (PCIG-GA-2011-293502).
Funding body: Career Integration Grants (CIG). Marie Curie Actions. European Commission.

Metabolic and biochemical effects of betaine on insulin sensitivity and exercise performance (SAF2011-28502).
Funding body: Spanish Ministry of Science and Innovation (MICINN).

Unraveling novel molecular mechanisms underlying the development of insulin resistance.
Funding body: European Foundation for the Study of Diabetes (EFSD), EFSD/Lilly Fellowship Programme.

Regulation and function of microRNAs in pancreatic islets.
Funding body: Spanish Ministry of Science and Innovation (MICINN).

Epigenetic control of gene expression in pancreatic islets.
Funding body: European Foundation for the Study of Diabetes (EFSD), EFSD/Lilly Fellowship Programme.